All Articles
Browse every published article, from the latest research to earlier analysis. Use the page numbers below to explore the complete archive.
Ventilation Duration Changed the Denominator in a Korean Midazolam Utilization Study
A claims analysis showed that ever receiving a sedative and the proportion of days receiving it can move differently.
Lorazepam as an Imaging Comparator: Similar Amygdala Effects Did Not Prove Equal Anxiety Relief
A small generalized-anxiety study compared a novel cholinergic modulator with lorazepam and placebo using brain responses to fearful faces.
Benzodiazepines Did Not Share the Antipsychotic Rhythm Association in This Cardiac-Arrest Study
An observational cardiac-arrest analysis found a psychotropic association driven particularly by antipsychotics, with a null benzodiazepine finding.
Lorazepam in a Neuroleptic Malignant Syndrome Case: Improvement Followed a Treatment Bundle
A case involving renal failure, lithium toxicity, and changing psychotropics cannot isolate lorazepam’s contribution to recovery.
Atropine Poisoning Discussion Distinguished Diazepam Symptom Control From Antidote Action
A pediatric medication-error report illustrates why a benzodiazepine’s supportive role should not be confused with reversal of the poisoning mechanism.
Hemorrhagic-Shock Rat Study: Midazolam Probe Kinetics Reflected the Resuscitation Context
An animal study found altered CYP protein expression and prolonged elimination of probe drugs after hemorrhage and resuscitation.
Diazepam and Ethanol in Poison-Center Clustering: Statistical Proximity Did Not Prove Interaction
A multivariate poison-center analysis grouped some diazepam and ethanol cases along a statistical axis, rather than measuring a combined drug effect.
Burning Mouth Chart Review: Small Subgroups Limit a Sex-Specific Clonazepam Claim
A retrospective dental study reported differing clonazepam response proportions by sex in a small burning-mouth subgroup.
Panic Disorder Caffeine Study Found No Correlation With Benzodiazepine Use
A case-control study found greater caffeine consumption in panic disorder but no correlation between caffeine intake and reported sedative use.
Oslo Recreational Poisonings: Benzodiazepines Were Common Within a Selected Prescription-Drug Subset
An emergency-clinic study found benzodiazepines in most prescription-related recreational poisoning cases, usually amid mixed exposure.
Lorazepam in Pregabalin-Associated Negative Myoclonus: Two Changes Preceded Recovery
An older patient’s involuntary postural lapses resolved after lorazepam administration and pregabalin discontinuation.
Clobazam Trial Reanalysis Found Fewer Seizure-Related Injuries, a Distinct Outcome From Seizure Counts
A post hoc analysis of a Lennox-Gastaut trial reported fewer seizure-related injuries among clobazam recipients than placebo recipients.
Triazolam in Primate Activity Monitoring: Movement Was a Sleep Proxy, Not Sleep Architecture
A primate study compared an implanted activity sensor with polysomnography during sleep-drug testing.
Epilepsy Tissue Showed Altered GABA-A Modulation: Receptor Composition Complicates Drug Response
A translational receptor study linked epilepsy tissue and experimental neuronal activity with changed modulation of GABA-A currents.
Bergamot Behavioral Effects Were Not Simply a Diazepam-Like Mechanism
A rodent study used serotonin-receptor probes to examine essential-oil effects that were not identical to diazepam’s behavioral profile.
ECG Changes After a Lorazepam-Treated Seizure: Temporal Proximity Did Not Identify the Cause
A case report illustrates competing explanations for cardiac findings after a seizure and several medication changes.
Sleep Medicines in Residential Youth Care: The Benzodiazepine Subgroup Was Much Smaller
A Norwegian registry study found greater sleep-medication dispensing in residential care, with benzodiazepines and Z-hypnotics comprising a small subgroup.
Majorcan Physician Survey: Reported Insomnia Follow-Up Was Not Audited Prescribing
A survey describes how family physicians said they managed insomnia, including benzodiazepine preferences and treatment review.
Diazepam Response in Visual-Presentation Status Epilepticus: EEG Supplied Crucial Context
A case report linked visual symptoms with continuous epileptiform activity and improvement after antiseizure treatment.
German Pediatric Sedation Survey: Frequent Midazolam Use Did Not Measure Adverse-Event Rates
A nationwide center survey described sedation resources and drug choices, but did not directly quantify complications.
Midazolam During a Post-Hysteroscopy Delirium Case: Recovery Had Multiple Possible Contributors
A case report describes midazolam among several treatments after postoperative unresponsiveness, without isolating its effect.
A GABRA1 Variant Shifted Diazepam Binding in Vitro Without Establishing a Clinical Dose Response
A functional genetics study found altered receptor behavior and diazepam binding in a laboratory model of a rare GABRA1 variant.
Benzodiazepines and Hepatic Encephalopathy: Claims Cohort Findings Need Causal Caution
A large Medicare cohort associated benzodiazepine exposure with incident hepatic encephalopathy and related hospitalization in people with cirrhosis.
Emergency Benzodiazepine Administration Was Not Associated With Delirium Duration in This Cohort
A secondary analysis found no significant benzodiazepine association with delirium duration, but few exposed patients limited its ability to detect one.
Sedative Knowledge Survey: Knowing Midazolam Is Not an Analgesic Was a Measured Item
A hospital survey found gaps in knowledge about sedatives, analgesics, and neuromuscular blockers, without directly measuring patient-care errors.
Benzodiazepine Premedication Predicted Postoperative Anxiety in a Scale-Validation Study
An observational study found an association between benzodiazepine premedication and postoperative anxiety, but was designed primarily to evaluate an anxiety scale.
Herbal Combination and Benzodiazepine Prescribing in Psychiatric Inpatients: A Nonrandomized Signal
A retrospective matched study associated Ze 185 prescribing with fewer benzodiazepine prescriptions, without proving that the herbal combination caused the difference.
Rat Diazepam EEG Analysis Changed When Movement State Was Separated
A quantitative EEG study used automated movement classification to distinguish drug effects from changes in how often rats moved.
Experimental Benzodiazepine-Site Analgesia Depended on Chloride Regulation
A preclinical neuropathic-pain study found that altered chloride handling limited the effect of a selective GABA-A ligand at higher doses.
A Healthy-Volunteer Midazolam Interaction Study Found No Meaningful PF-06751979 Effect
An early-phase development paper reported no clinically meaningful midazolam pharmacokinetic change under one tested PF-06751979 regimen.