All Articles
Browse every published article, from the latest research to earlier analysis. Use the page numbers below to explore the complete archive.
Korean Fall Study Linked Long-Acting Benzodiazepine Prescriptions With Hospital-Treated Events
A case-crossover association supports attention to medication timing without proving the cause of an individual fall.
A 2022 Epilepsy Interaction Commentary Distinguished Midazolam Routes During Ritonavir Treatment
Historical interaction recommendations illustrate why route and persistence of enzyme inhibition matter in a medication timeline.
Lorazepam Changed TMS Excitability Measures Without Validating an Impairment Test
A measurable cortical drug effect is different from a validated measure of driving ability or legal capacity.
Dental Implant Cohort Linked Sedation With Follow-Up Attendance, Not Proven Implant Protection
A retrospective association with better maintenance attendance does not establish that midazolam improves implant biology.
Zolpidem Catatonia Case Found Initial Improvement With Limited Durability
A transient response after unsuccessful benzodiazepine treatment did not establish sustained benefit from zolpidem.
Benzodiazepine Deprescribing Overview Emphasizes Support Beyond a Prescription Change
Reducing inappropriate prescribing involves patient and clinician behavior as well as the written dose schedule.
Benzodiazepine Hypersensitivity Review Highlights Uncertain Mechanisms and Testing
A perioperative reaction after a benzodiazepine does not by itself establish an immune-mediated allergy.
Gabapentinoid Poisoning Study Found Elevated Risk Before Treatment Began
The pre-treatment period is essential to interpreting an association between gabapentinoids, benzodiazepine overlap and poisoning.
Gallbladder Surgery Cohort Found Faster Recovery Without Strict Confounding Control
Remimazolam was associated with earlier extubation than midazolam in a retrospective surgical comparison.
Alcohol Cessation and Mania Case Shows Why Collateral History Changes Interpretation
A short diazepam course did not determine whether the patient’s underlying illness was mania or alcohol withdrawal.
Postoperative Cancer ICU Trial Kept Sedation Targets Separate From Later Outcomes
A small randomized trial found similar sedation measures with different adverse-event frequencies, without establishing a survival or ventilation benefit.
Sepsis Mouse Transcriptomics Identified Remimazolam Correlates Rather Than Proven Targets
A molecular study associated remimazolam treatment with inflammatory gene patterns in a murine sepsis model.
Leigh-Syndrome Anesthesia Case Required Recovery and Airway Management After Remimazolam
A spinal-surgery case described useful anesthetic monitoring alongside postoperative respiratory-management challenges.
Human Orthostatic-Tremor Baseline Study Did Not Test Clonazepam Efficacy
Frequent clonazepam prescribing in a movement-disorder cohort did not establish treatment superiority.
Angelman Movement Study Relied on Caregivers for Benzodiazepine Benefit Reports
A phenotype study identified overlapping movement disorders, while reported medication benefit remained observational.
Akathisia Network Review Rated Benzodiazepine Evidence as Uncertain
A systematic review suggested possible short-term benefit while emphasizing low confidence and missing long-term evidence.
Dry-Mouth Study Found Mixed Salivary Associations in Psychiatric Polypharmacy
Poorer oral-health findings among psychiatric outpatients did not establish a uniform benzodiazepine-induced reduction in every type of saliva.
Aging EEG Review Warned Against Treating Alpha Power as a Drug-Independent Depth Scale
A narrative review explained that age and hypnotic choice both influence EEG features used during anesthesia.
Aeromedical Sedation Review Found No Recorded Sedation-Depth Assessments
A transfer-service audit described rescue boluses and infusion practices, while missing assessment data limited conclusions about adequate sedation.
Liver-Disease Withdrawal Cohort Compared Phenobarbital With Different Benzodiazepine Groups
A propensity-weighted ICU study found comparator-dependent results for severe alcohol withdrawal in alcohol-associated liver disease.
Fatal-Crash Psychotropic Findings Did Not Establish Drug-Caused Suicidal Intent
A Finnish fatal-crash study linked psychiatric history with toxicology and reconstructed intent, but drug detection could not explain why a particular crash occurred.
Deprescribing Cost Study Compared Six-Month Discontinuers With Continuers
A primary-care cohort suggested favorable cost and quality-of-life results after benzodiazepine discontinuation, without demonstrating randomized economic savings.
COVID-ARDS Sedation Cohort’s Shorter Stay Was Confounded by Very High Mortality
A historical ICU comparison found more intensive sedation in COVID-ARDS, while shorter stays could not be interpreted as faster recovery.
Canine Co-Induction Review Separated Propofol Dose Savings From Cardiorespiratory Benefit
A veterinary evidence summary found inconsistent propofol dose reductions with benzodiazepine co-induction and no established reduction in cardiorespiratory adverse events.
Intermittent Diazepam Altered Rat Seizure Clusters Without Proving Human Disease Modification
A small epilepsy experiment found persistent changes in seizure-cluster patterns after intermittent diazepam, alongside rebound findings that complicate interpretation.
Patient-Controlled Remimazolam Trial Tested Delivery Strategy as Well as Drug
Patient-controlled sedation improved selected outcomes under spinal anesthesia, but both groups received remimazolam.
Elderly Polypectomy Trial Found Slower Recovery Despite Less Hypotension
A trial of continuous remimazolam illustrated a tradeoff: lower hypotension frequency did not coincide with faster recovery than propofol.
Clotiazepam Case Described Relief of Respiratory Dyskinesia in Vascular Parkinsonism
One case reported improvement in abnormal respiratory movements after clotiazepam, but did not establish a standard treatment or a general safety advantage.
Hyperlipidemia Cohort’s Remimazolam Delirium Association Remained Observational
A retrospective surgical cohort found less delirium with remimazolam, but statistical target-trial methods did not make drug assignment randomized.
Psilocybin–Midazolam EEG Pilot Separated Electrical Patterns From Remembered Experience
An exploratory study recorded changing brain signals during combined psilocybin and midazolam administration, without validating a universal marker of consciousness or memory.