Cirrhosis Endoscopy Trial Found Similar Two-Hour Stroop Results Despite Slower Recovery With Midazolam

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A small randomized study separated short cognitive testing from awakening and recall. Similar performance at one time point did not mean identical recovery in every respect.

The measured outcomes

Sixty patients with advanced cirrhosis received midazolam, propofol, or a combination for upper endoscopy. Stroop measures before and two hours afterward did not significantly worsen or differ across groups.

Recovery was longest with midazolam, while awakening and memory measures differed. Patient satisfaction was similar despite these distinct findings.

One cognitive test is incomplete

The authors identified use of a single cognitive tool and absence of long-term assessment as limitations. A small selected sample cannot exclude uncommon complications or every cognitive deficit.

The trial cannot establish a universal safe discharge time or driving readiness. Forensic interpretation should retain baseline liver disease, drug sequence, time since administration, and the exact assessed function. A reassuring Stroop result should not be converted into proof of complete functional recovery.

Source paper

Original analysis of the supplied journal article, identified as PMC6856546.

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