All Articles
Browse every published article, from the latest research to earlier analysis. Use the page numbers below to explore the complete archive.
Adult Oromucosal Midazolam Review Described Exposure Bridging
Matching exposure across populations is a different evidence route from a new outcome trial.
Clobazam–Stiripentol Modeling Predicted a Genotype-Dependent Metabolite Interaction
Parent-drug and active-metabolite exposure can change differently.
Phantosmia Followed a Perioperative Clonazepam Interruption in One Case
An unusual sensory symptom can have a medication-timing hypothesis without being diagnostically specific.
ERCP Meta-Analysis Found More Movement Alongside Less Hypoxia
A favorable safety profile can contain meaningful trade-offs.
Free-Flap Sedation Pilot Used Less Colloid Without Proving Better Flap Perfusion
A management difference is not the same as a measured organ-outcome benefit.
Hernia-Surgery Trial Assessed Emergence Delirium With a Pediatric Scale
A reduction in an early emergence endpoint is narrower than prevention of all postoperative cognitive problems.
Hand-Holding and Conversation Were Added to Midazolam, Not Compared With Its Absence
Nonpharmacological support can be tested as an adjunct within a shared medication strategy.
A Two-Center Rodent Stroke Trial Tempered Earlier Hybrid-Molecule Findings
Broader preclinical testing can produce smaller or inconsistent effects than initial experiments.
Adding Remimazolam to Ciprofol Changed a Combination Strategy
A favorable mixed regimen cannot be attributed to one ingredient in isolation.
Trimester-Specific Birth Associations Persisted in a Sibling Analysis
A sibling comparison reduces some shared-family confounding without eliminating all confounding.
Body-Weight Normalization Changed the Apparent Remimazolam Dose Difference
Milligrams per kilogram depends on which body-weight quantity forms the denominator.
Screening Colonoscopy Discharge Time Included the Procedure Itself
A shorter medication-to-discharge interval is not purely a clearance measurement.
Helsinki Pharmacist-Led Deprescribing Interviews Described Perceived Efficiency
Professionals’ experience of saved time is not a measured economic or clinical effect.
A Sleep Formulary Changed Prescribing Systems Alongside Medication Choice
A hospital-wide before-and-after change cannot isolate the effect of one substitute drug.
Dental Midazolam Dose Associations Reflected Titrated Clinical Practice
A prescribed amount can be an outcome of treatment decisions rather than a fixed measure of sensitivity.
Low-Dose Remimazolam Changed Six-Hour Nausea but Not the Twenty-Four-Hour Endpoint
The assessment window can determine whether an apparent antiemetic benefit is present.
Chronic Hypnotic Users Had Different Sleep Architecture in an Observational Comparison
More time asleep and normal sleep architecture are different questions.
Diazepam–rTMS Combination Reduced a Cell-Calcium Signal
A cellular fluorescence endpoint is not a patient seizure-control rate.
Vatinoxan Changed Cortex-to-Plasma Ratios in a Midazolam-Containing Rat Regimen
A tissue-to-plasma ratio and an absolute tissue concentration are different measurements.
Gastroscopy Hemodynamic Study Measured Cardiac Output as Well as Pressure
Blood pressure is only one part of circulatory assessment.
Mental-Health-Ward Deprescribing Interviews Identified an Interface Problem
Medication continuation can reflect service processes as well as patient symptoms.
Dental-Implant Sedation Separated Alertness Scores From Discharge Delay
Being alert on a scale and meeting all discharge conditions are different milestones.
Lithotripsy Inflammatory Markers and Early Responsiveness Gave Different Recovery Signals
Lower biomarkers do not guarantee greater alertness immediately after surgery.
Walking Five Minutes After Endoscopy Was a Specific Recovery Endpoint
Early ambulation does not establish recovery of every cognitive function.
Pediatric Neurosurgical ED90 Was an Uncertain Moderate-Sedation Estimate
A high-response dose estimate does not guarantee adequate or complication-free sedation.
A Delphi Deprescribing Study Ranked Strategies Rather Than Testing Cessation
Agreement about priorities is not evidence that an intervention works.
Serum Diazepam–Metabolite Validation Was Not an Impairment-Threshold Study
Analytical accuracy and clinical interpretation require separate evidence.
Equine Sedation Endpoints Did Not All Show the Same Combination Advantage
Head position, stimulus response and muscle relaxation are different measures.
Day-Surgery Remimazolam Was Studied Without Routine Flumazenil
Recovery results should distinguish spontaneous emergence from pharmacological reversal.
Pediatric Emergence-Agitation Comparison Also Changed Route of Premedication
A drug comparison can simultaneously be a route-and-regimen comparison.